Epidemiología molecular de la tuberculosis

Deciphering the Tangible Spatio-Temporal Spread of a 25-Year Tuberculosis Outbreak Boosted by Social Determinants. López MG, Campos-Herrero MI, Torres-Puente M, Cañas F, Comín J, Copado R, Wintringer P, Iqbal Z, Lagarejos E, Moreno-Molina M, Pérez-Lago L, Pino B, Sante L, García de Viedma D, Samper S, Comas I. Microbiol Spectr. 2023 Feb 14;11(2):e0282622. doi: 10.1128/spectrum.02826-22. PMID: 36786614 Free PMC article.

Rapid Identification of Lineage and Drug Resistance in Clinical Samples of Mycobacterium tuberculosis. Comín J, Viñuelas J, Lafoz C, Cebollada A, Ibarz D, Iglesias MJ, Samper S. Microorganisms. 2023 May 31;11(6):1467. doi: 10.3390/microorganisms11061467. PMID: 37374968 Free PMC article.

Transcriptomic profile of the most successful Mycobacterium tuberculosis strain in Aragon, the MtZ strain, during exponential and stationary growth phases. Comín J, Campos E, Gonzalo-Asensio J, Samper S.

Millán-Lou MI, López C, Bueno J, Pérez-Laguna V, Lapresta C, Fuertes ME, Rite S, Santiago M, Romo M, Samper S, Cebollada A, Oteo-Iglesias J, Rezusta A. Successful control of Serratia marcescens outbreak in a neonatal unit of a tertiary-care hospital in Spain. Enferm Infecc Microbiol Clin (Engl Ed). 2022 May;40(5):248-254. doi: 10.1016/j. eimce.2021.05.014. PMID: 35577443.

Comín J, Otal I, Samper S. In-depth Analysis of IS6110 Genomic Variability in the Mycobacterium tuberculosis Complex.
Front Microbiol. 2022 Feb 24;13:767912. doi: 10.3389/fmicb.2022.767912. PMID: 35283840; PMCID: PMC8912993.

Comín J, Cebollada A, Ibarz D, Viñuelas J, Sahagún J, Torres L, Iglesias MJ, Samper S. Analysis of the twenty-six largest outbreaks of tuberculosis in Aragon using whole-genome sequencing for surveillance purposes. Sci Rep. 2022 Nov 5;12(1):18766. doi: 10.1038/s41598- 022-23343-1. PMID: 36335223; PMCID: PMC9637126.

Comín J, Cebollada A; Aragonese Working Group on Molecular Epidemiology of Tuberculosis (EPIMOLA); Samper S.
Estimation of the mutation rate of Mycobacterium tuberculosis in cases with recurrent tuberculosis using whole genome sequencing. Sci Rep. 2022 Oct 6;12(1):16728. doi: 10.1038/s41598-022-21144-0. Erratum in: Sci Rep. 2023 Feb 27;13(1):3367. PMID: 36202945; PMCID: PMC9537313.

Comín J, Madacki J, Rabanaque I, Zúñiga-Antón M, Ibarz D, Cebollada A, Viñuelas J, Torres L, Sahagún J, Klopp C, Gonzalo-Asensio J, Brosch R, Iglesias MJ, Samper
S. The MtZ Strain: Molecular Characteristics and Outbreak Investigation of the Most Successful Mycobacterium tuberculosis Strain in Aragon Using Whole-Genome Sequencing. Front Cell Infect Microbiol. 2022 May24;12:887134. doi: 10.3389/fcimb.2022.887134. PMID: 35685752; PMCID: PMC9173592.

Gonzalo-Asensio J, Pérez I, Aguiló N, Uranga S, Picó A, Lampreave C, Cebollada A, Otal I, Samper S, Martín C. New insights into the transposition mechanisms of  IS6110 and its dynamic distribution between Mycobacterium tuberculosis Complex lineages. PLoS Genet. 2018 Apr 12;14(4):e1007282. doi: 10.1371/journal.pgen.1007282. PubMed PMID: 29649213.

Arregui S, Iglesias MJ, Samper S, Marinova D, Martin C, Sanz J, Moreno Y. Data-driven model for the assessment of Mycobacterium tuberculosis transmission in evolving demographic structures. Proc Natl Acad Sci U S A. 2018 Apr 3;115(14):E3238-E3245. doi: 10.1073/pnas.1720606115. PubMed PMID: 29649213.

Samper S, González-Martin J. Microbiological diagnosis of infections caused by the genus Mycobacterium. Enferm Infecc Microbiol Clin. 2018 Feb;36(2):104-111. doi: 10.1016/j.eimc.2017.11.009. PubMed PMID: 29287920.

Pérez-Laguna V, García-Luque I, Ballesta S, Pérez-Artiaga L, Lampaya-Pérez V, Samper S, Soria-Lozano P, Rezusta A, Gilaberte Y. Antimicrobial photodynamic activity of Rose Bengal, alone or in combination with Gentamicin, against planktonic and biofilm Staphylococcus aureus. Photodiagnosis Photodyn Ther. 2018 Mar;21:211-216. doi: 10.1016/j.pdpdt.2017.11.012. PubMed PMID: 29196246.

2019

Moreno B B, R.;Andres-Lasheras, S.;Sevilla, E.;Samper, S.;Morales, M.;Vargas, A.;Chirino-Trejo, M.;Badiola, J. J. Antimicrobial Susceptibilities and Phylogenetic Analyses of Enterococcus hirae Isolated from Broilers with Valvular Endocarditis. Avian Dis 2019; 63 (2):   318-324. DOI 10.1637/11986-102418-Reg.1. ISSN: 0005-2086.

Perez-Lago L C-H, M. I.;Canas, F.;Copado, R.;Sante, L.;Pino, B.;Lecuona, M.;Gil, O. D.;Martin, C.;Munoz, P.;Garcia-de-Viedma, D.;Samper, S. A Mycobacterium tuberculosis Beijing strain persists at high rates and extends its geographic boundaries 20 years after importation. Sci Rep 2019; 9 (1): 4687. DOI 10.1038/s41598-019-40525-6. ISSN: 2045-2322.

2016

Sagasti S, et al. In-depth analysis of the genome sequence of a clinical, extensively drug-resistant Mycobacterium bovis strain. Tuberculosis (Edinb).100:46-52 (2016)

Nebreda T,  et al. Peritoneal tuberculosis due to Mycobacterium caprae. IDCases. 5;4:50-2 (2016)

Nikolayevskyy V, et al. External Quality Assessment for Tuberculosis Diagnosis and Drug Resistance in the European Union: A Five Year Multicentre Implementation Study. PLoS One. 7;11(4):e0152926(2016)

Molina-Moya B , et al. Evaluation of GenoFlow DR-MTB Array Test for Detection of Rifampin and Isoniazid Resistance in Mycobacterium tuberculosis. J Clin Microbiol.;54(4):1160-3 (2016)

Millán-Lou MI, , et al. Mycobacterial diversity causing multi- and extensively drug-resistant tuberculosis in Djibouti, Horn of Africa. Int J Tuberc Lung Dis. 20, 150-153 (2016)